Albendazole Bolus 2500 mg
Albendazole yog ib qho khoom siv anthelmintic uas belongs rau pab pawg ntawm benzimidazole-derivatives nrog kev ua haujlwm tawm tsam ntau yam kab mob thiab ntawm qib ntau dua kuj tiv thaiv cov neeg laus theem ntawm daim siab fluke.
Pharmacological Action
Albendazole ua ke nrog eelworm's microtubule protein thiab ua lub luag haujlwm.Tom qab albenzene ua ke nrog β-tubulin, nws tuaj yeem tiv thaiv dimerization ntawm albenzene thiab α tubulin sib sau ua ke rau hauv microtubules.Microtubules yog cov qauv tsim ntawm ntau lub cell units.Albendazole's affinity rau nematodes tubulin yog ho siab tshaj qhov affinity ntawm mammalian tubulin, yog li toxicity rau mammalian me me.
Cov lus qhia
Prophylaxis thiab kev kho mob ntawm worminfection nyob rau hauv nyuj thiab nyuj zoo li:
Gastrointestinal kab mob:Bunostomum, Cooperia, Chabertia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides thiab Trichostrongylus spp.
Lub ntsws worms:Dictyocaulus viviparus thiab D. filaria.
Tapeworms:Monieza swb.
Mob plab:Tus neeg laus Fasciola hepatica.
Albendazole tseem muaj cov nyhuv ovicidal.
Contraindications
Kev tswj hwm hauv thawj 45 hnub ntawm cev xeeb tub.
Cov teebmeem
Cov tshuaj tiv thaiv hypersensitivity.
Kev noj tshuaj
Rau kev tswj qhov ncauj.
Rau roundworms, tapeworms:
nyuj / nyuj / nees / yaj / tshis: 5mg / kg lub cev hnyav
Aub / miv: 10 mus rau 25mg / kg lub cev hnyav
Rau flukes:
nyuj / nyuj: 10mg / kg bodyweight
Yaj / tshis: 7.5mg / kg lub cev hnyav
Nqaij nyuj thiab nyuj: 1 bolus ib 300 kg.lub cev hnyav.
Rau lub siab-fluke:
1 bolus rau 250 kg.lub cev hnyav.
Ceeb toom
Khaws kom deb ntawm cov menyuam yaus.
Lub Sijhawm Ua Haujlwm
3 xyoo.
Lub Sijhawm Them Nyiaj
- Rau nqaij:12 hnub.
- Rau tej yam:4 hnub.
Cia
Khaws rau hauv qhov txias txias, qhuav qhov chaw tiv thaiv los ntawm lub teeb.
Rau Veterinary Siv nkaus xwb, Khaws kom deb ntawm cov menyuam yaus
